According to the Federal Register, there have been 209 executive orders signed in 2025.
Of those, 12 executive orders stand out as having a direct impact on healthcare in some manner.
2025 Healthcare Related Executive Orders
- January 24, 2025 – Enforcing the Hyde Amendment
Primarily patients and providers.
Reinforces restrictions on federal funding for elective abortions, impacting hospitals and health systems receiving federal grants or Medicaid reimbursements. - January 28, 2025 – Protecting Children from Chemical and Surgical Mutilation
Providers and patients.
Directs the Department of Health and Human Services to halt federal funding and medical guidance supporting gender transition procedures for minors. - February 13, 2025 – Establishing the President’s Make America Healthy Again Commission
Payers, providers, and patients.
Creates a federal commission led by HHS to coordinate interagency efforts on preventive health, disease management, and promoting affordable wellness initiatives. - February 14, 2025 – Keeping Education Accessible and Ending COVID-19 Vaccine Mandates in Schools
Patients (students and families).
Prohibits federal funds to schools enforcing COVID-19 vaccination mandates, emphasizing parental rights and individual health choice. - February 18, 2025 – Expanding Access to In Vitro Fertilization
Patients and payers.
Seeks to reduce costs and increase insurance coverage options for IVF treatments through regulatory relief and expanded awareness initiatives. - February 25, 2025 – Making America Healthy Again by Empowering Patients with Clear, Accurate, and Actionable Healthcare Pricing Information
Payers and patients.
Expands hospital and insurer transparency rules, requiring full disclosure of negotiated care prices to reduce costs and empower consumer decision-making. - April 15, 2025 – Lowering Drug Prices by Once Again Putting Americans First
Payers and patients.
Directs agencies to secure “most-favored-nation” drug prices, ensuring Americans pay no more than citizens of other developed nations. - May 5, 2025 – Regulatory Relief to Promote Domestic Production of Critical Medicines
Providers and payers. Eases regulations to boost domestic manufacturing of essential medicines, reducing reliance on foreign supply chains and preventing shortages. - May 5, 2025 – Improving the Safety and Security of Biological Research
Providers and public health stakeholders.
Establishes safety standards for federally funded labs to mitigate biosecurity risks and strengthen public health research integrity. - May 12, 2025 – Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients
Payers and patients.
Ensures domestic drug prices match those paid by peer nations, cutting costs for consumers and insurers. - August 13, 2025 – Ensuring American Pharmaceutical Supply Chain Resilience by Filling the Strategic Active Pharmaceutical Ingredients Reserve
Providers and payers.
Establishes a strategic reserve of critical drug ingredients to stabilize supply for hospitals and pharmacies in case of shortages or international disruptions. - September 30, 2025 – Unlocking Cures for Pediatric Cancer With Artificial Intelligence
Providers and patients.
Directs federal agencies to use AI to accelerate pediatric cancer research, drug development, and treatment personalization.
Q1. When does the 2025 hospital price-transparency executive order go into effect?
The order gave HHS 90 days to propose regulations; CMS will set final compliance dates in the ensuing rulemaking cycle, likely beginning in calendar year 2026.
Q2. Do the 2025 executive orders on drug pricing replace the Inflation Reduction Act rules?
No. The April 15 and May 12 EOs add “most-favored-nation” pricing requirements on top of the IRA’s negotiation and rebate provisions. CMS will align both frameworks in forthcoming guidance.
Q3. How should hospitals prepare for the new federal biosafety standards in 2025?
Facilities should review BSL classifications, update incident-reporting protocols, and conduct mock inspections ahead of anticipated NIH and CDC site visits within 12 months of the May 5 order.
Q4. What is the timeline for new IVF coverage regulations under the 2025 executive order?
HHS and Treasury must publish proposed rules within six months of the Feb 18 order, with final payer-coverage requirements expected by late 2025 or early 2026.
Q5. Will schools lose funding if they keep COVID-19 vaccine mandates after the 2025 executive order?
The Feb 14 EO bars federal education funds to institutions that maintain COVID-19 vaccination requirements, reinforcing parental choice on immunizations.
Learn more about price transparency regulations & download a free Healthcare Price Transparency Compliance Kit.
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